Advanced Modular Bioreactors

Bio Bench Advanced is a new concept of Modular Bioreactors suitable for various vessels type and size.

Advanced Modular Bioreactors

Overview

Our advanced modular bioreactor series represents the latest advancements in automation, software and mechanical engineering applied to the bioprocess industry. Industrial standard technologies, high-flexibility, modularity, easy upgrades and replacements, guaranteed long-term spare part availability and after-sales service distinguish our modular bioreactors from the competition.

Smart Design

  • Pilot scale culture vessels are available in bacteriological or cell cultivation configurations in the following sizes: 20, 30, 40, 50, 70, 80, 100, 130, 150, 200, 250, 300, 400 and 500 litre volume w/v
  • Leading industry components for automation, electronics, sensors, valves and gas mixing, among others, offer quality without compromise
  • Piping module design eliminates casual operator contact
  • Powerful SCADA software to simultaneously manage multiple bioreactors
  • Fully automatic in-situ sterilisation with integrated steam generator
  • Integrated or external CIP in place cleaning system
  • Modular design and interconnectivity with external devices give the possibility of individual solutions.
Advanced Modular Bioreactors

Features

  • BioController module with industry leading PLC hardware, ModBus and Ethernet communication protocols to simplify and accelerate single and parallel bioreactor operations
  • Enhanched sensors capability integrating Online Biomass and Gas Analyzers, Automated samplers, HPLC, Mass Spec and othersGas mixing module supports 4-8 or more integrated massflow controllers per vessel, automated gas control strategy for cell culture or fermentation applications
  • Peristaltic pump module with 4-8 or more fix and variable programmable pumps per vessel with bi-direction flow for high precision dosing
  • Thermo module with built-in Chiller in a water saving closed loop. Accurate temperature control for single wall and water jacketed bioreactors

Volumes

Autoclavable vessels: 100-300-500 mL, 1-2-3-5-7-10-15-20 Litres
SUB Disposable vessels: 3-10-20-30-50 Litres

Advanced Modular Bioreactors

Decisive Advantage

The powerful modular controller allows you to interchange different types of autoclavable vessels from 100 mL to 30 litres, Disposable from 250 mL to 75 litres w/v, and SIP stainless steel from 1 litre to 100 litres w/v.

Each module (controller, gas mixing, pumps, thermo loop) can be upgraded, exchanged and replaced at any time without the need for an expert technician.

The communication between the various modules via fieldbus. This industrial measuring technique allows the measured values to be provided quickly and securely to the central controller that automates the machine.

The system also offers great benefits in terms of the reliability of the machine and fast installation. A modern operating concept with Bioflex Advanced SCADA Software. Each Advanced system features an innovative web server, which not only allows the system status and measurement data to be displayed, but the command and configuration at the same time as well.

The user can also rely on another big advantage: since the user interface is web-based, no additional software is required. All that is needed is a normal PC or laptop with an installed browser. In this way, mobile applications and remote control commands can also be implemented, reducing start-up and maintenance times and, as a result, costs.

Key Advantages

  • Compact design, small footprint WxD 280x400mm or 100×400 inches (US)
  • Suitable for glass and single use vessel
  • Great accuracy and reliability with adaptive P.I.D. control
  • Integrated Data Management and Data Acquisition Software
  • Touch panel PC or conventional PC workstation
  • Integrated heating and cooling system with the Solida BIO-CHILLER
  • Real-time industrial controller, reconfigurable IO Modules, Ethernet expansion
  • Simplicity of installation, programming and maintenance
  • SensorFlash® non-volatile memory to save your bioprocess data
  • Certified for GLP and GMP classified environments
  • Sales and service available worldwide

Key Aspects

  • Expandability of individual modules for managing from 1 to 36 bioreactors in parallel
  • Interchangeability of modules, easy testing of modules
  • Simplified interfaces through which the modules communicate with each other
  • Minimum waiting times for replacement and/or maintenance

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